WE are hear about the big companies in the media but it is small businesses that drive the economy. So use your smallness to your advantage.
The biggest advantage of being small is that you can be fleet of foot. Agility is important in todays ever changing business world. When a new trend starts growing legs it is easier if you are small and nimble to change direction and leverage on first mover advantage.
Most of the innovation that we see from big companies comes from their purchase of smaller, innovative companies with ideas. When you are large physically you don't move as quickly as some one who is small and agile (think energetic children here).
Just remember Small is Beautiful and can be very Profitable as well.